After getting the MTHFR testing back we began methylfolate and P5P. He had already been on methylcobalmin for months which was helpful. Initially he complained that after he took his Methylfolate/P5P supplement it always made him have to pee. I haven’t heard this complaint in a while so I think that stopped.
However, what we have noticed of lately, and it’s taken me some time to figure this out…is he is irritable an awful lot of the time. This is a fairly recent problem and we were attributing it to puberty initially but as I began thinking….even puberty isn’t this irritable!
Just not himself at all, argumentative, and didn’t want to do anything….even things he normally liked. He was obviously feeling bad and I couldn’t figure out why.
It dawned me on two days ago…what about the methylation supplements?!?!?
I did not respond well to methylfolate but he seemed just fine when we started it. So I assumed we were go to continue giving it to him. That was some 9 months ago but what if what’s good then isn’t good now?
I began searching the web and found an article by Ben Lynch describing the problems some people have with methylfolate. He talks about how someone could do well initially and then it can all fall apart.
So on a hunch I stopped giving his morning 800 mcg methyfolate supplement, just to see.
Guess what? He is back to himself!!
He is still taking his MB12 because he was on that prior to the methylfolate and did well on it for over a year.
His CBC is indicating he is no B12 anemic anymore…hmm..perhaps he doesn’t need as much folate?