The results of our LDN and antivirals

We had our follow-up with the doctor today to go over labs and touch base on progress after changes made in March following his lab results. This time we checked his thyroid levels, CBC with Diff, DHEA, Ferritin, Insulin, Comp Metabolic 14 Panel, thyroid antibodies.

Just to refresh what’s been going on this past few months we have been treating him for a viral and low immune system issue, hypothyroidism, anemia and nutritional deficiencies.

We were very pleased with the results because he is making progress! So that long list of antivirals and immune support he’s been taking daily since March has worked. His CBC with Diff is normal for the first time since 2011. His thyroid antibodies have come down to a normal range. Would be nice to see them even lower but from a diagnostic standpoint he no longer has “Hashimoto’s autoimmune hypothyroid”.

He is however, still hypothyroid on 1/2 grain of NatureThroid so we will be working to increase his dose slowly and repeating labs in a few months.

Ferritin came up nicely to 53 so we can cut back and phase out his iron supplement. Hopefully, he holds the levels, but if not, we might need to start it again.

DHEA is normal for his age now and ironically we never supplemented this. It isn’t really safe to use in children prior to the completion of puberty. All we did do was support his adrenal glands with adrenal cortex glandular, and give him thyroid hormone…that alone reduces the stress on the adrenal glands so they can make more DHEA!

I’m excited that our remaining supplement list is much lower now.

I also wanted to share that we have seen a significant reduction in anxiety and have been

Compounded Troches (Gummies) Image Credit: http://www.betterlivingmedical.com

able to reduce his theanine to once a day since raising thyroid meds. It is so amazing how adrenal symptoms are so often driven by low thyroid hormones and so easily corrected with a little thyroid hormone. We do need to finish out his Low dose naltrexone therapy for another 2 months though but he has no symptoms from taking it and doesn’t mind the gummies. (compounding pharmacies are a blessing, not on my wallet but eh..I’ll pick my battles!

I still have him on Citicholine for other reasons and I will continue reading about MTHFR because it my next post I talk about the problem we ran into with methylfolate.

Now we just hope these improvements stick off of the antivirals.

Advertisements

Low Dose Naltrexone

We began at 1 mg of low dose naltrexone at bedtime as per the doctor’s instructions in March. Generally the starting dose is higher but she wants to eliminate/reduce any side effects if possible. From what I read there are usually few side effects and they usually subside in the first week.

The primary symptoms usually reported are sleep disturbances which can be insomnia or vivid dreams.

His first night at 1 mg, he did report bad dreams and he wasn’t too happy about it. The next night I only gave half of a milligram instead. That seemed to eliminate the bad dreams but he is having trouble getting to sleep. He either up late or waking up in the middle of the night.

After 2 weeks I increased the dose to 1 mg as per the doctor. So nightmares are back and he’s not happy at all about that. Who would be? I talked to the doctor again to clarify how long and if that will go away. She suggested we move dosing to daytime which would entirely eliminated the issue.

That did eliminate the issue thankfully. Today we moved up to 1.5 mg. Our target dose is 3.5mg. In three months blood work will be done to see if the viral issue is gone.

We are also using immune supporting herbs and antiviral herbs daily.

I am adding lysine now that I found one that dissolves in juice easily.  Ironically on all these antivirals and there is no yeast overgrowth so that’s a win I owe to chelation.

I was going to also add in olive leaf but I cannot gag down the olive leaf tincture I bought…so that’s not going to work. We have not started niacinamide yet but it’s on my radar because of its usefulness in autoimmunity but I do have him on selenium daily.

I will post when I have more conclusive results from doing the antiviral/immune regulation treatment. I suspect I won’t know more until summer when we see his blood work. To date, sensory is unchanged but hopefully this will help his immune system and thyroid function.

Viruses? Still?

Viruses? Still?

We went for our follow-up visit with our holistic doc. We first saw her in the fall of 2016 and after some supplementation it was time to repeat some blood work and see where to go next.

I was fairly surprised at the blood results really. Some of his deficiencies are improving which is great. Vitamin D is up to 60, so we can cut the dose back to 5,000 IU per day. Iron still needs some work but it’s a lot better.

Of course his DHEA and pregnenolone are still low since he isn’t taking those, but they have gone up from the previous test. His morning cortisol is also excellent thanks to adrenal cortex glandular.

We have reduced his insulin and glucose but they need to come down further. So we will keep going with the chromium with meals and protein in his diet.

We need to add in sea salt to his water.

The real kicker here was his labs from November showed low neutrophils and high lymphocytes. The doctor thought maybe he was getting over a virus which I thought was odd because he hadn’t been sick. Well his new labs show even lower neutrophils* and higher lymphocytes and he hasn’t been sick. Couple that in with thyroid antibodies and the doctor suspects there is an underlying viral problem causing autoimmunity.

When I saw his new labs I had a flashback because I knew I had seen this before. I went over his old labs and sure enough in 2010 things were normal but in 2011, we saw neutropenia and high lymphocytes. (absolute neuts went from 3.9-1.5 which is why we stopped using DMSA)

After those abnormal 2011 labs I did an antiviral protocol for him. Which is why I’m surprised to see a viral problem.

It seems that might not matter because you can get a virus at any time and if you’re immune system isn’t strong enough to clear it….well, it’s going to stick around for a while. It is also possible he was exposed to a different virus recently. In either case, he’s had this lab profile longer than is normal for a passing cold or virus. It also lines up with the slightly elevated TSH I’ve been seeing the past few years.

So my new marching orders are to add:

I’m also considering Lysine for suspected Epstein Barr since it’s most associated with causing thyroid antibodies.

I am further considering niacinamide which is great for autoimmunity. I may end up  repeating our previous antiviral protocol with olive leaf and Virastop. (now called Enzyme Defense). I’m not sure.

The doctor has recommend Low Dose Naltrexone at 1mg at bedtime for 3 months. Then she wants to re-test him.  LDN makes has a great track record with correcting autoimmunity. (I might be next then…hmm?)

The key here is going to getting more supplements into him.


*low absolute neutrophils is covered in Fight Autism and Win Second Edition. The incidence of neutropenia on blood work is contradictory for the use of DMSA for chelation.